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Scientists have created synthetic organisms that can self-replicate. Known as “Xenobots,” these tiny millimeter-wide biological machines now have the ability to reproduce — a striking leap forward in synthetic biology.

Published in the Proceedings of the National Academy of Sciences 0, a joint team from the University of Vermont, Tufts University, and Harvard University used Xenopus laevis frog embryonic cells to construct the Xenobots.

Their original work began in 2020 when the Xenobots were first “built.” The team designed an algorithm that assembled countless cells together to construct various biological machines, eventually settling on embryonic skin cells from frogs.

Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus (HIV).

The HIV epidemic has been overlooked during the COVID-19 pandemic but represents a critical and ongoing threat to with an estimated 1.5 million new infections in the last year alone.

Drug developers and research teams have been searching for cures and new treatment modalities for HIV for over 40 years but are limited by their understanding of how the virus establishes infection in the . How does this small, unassuming virus with only 12 proteins—and a genome only a third of the size of SARS-CoV-2—hijack the body’s cells to replicate and spread across systems?

Computer scientists at the University of California San Diego are showing how soil microbes can be harnessed to fuel low-power sensors. This opens new possibilities for microbial fuel cells (MFCs), which can power soil hydration sensors and other devices.

Led by Department of Computer Science and Engineering (CSE) Assistant Professor Pat Pannuto and Gabriel Marcano, a Ph.D. student working with Pannuto, this research was presented today at the first Association for Computer Machinery (ACM) Workshop on No Power and Low Power Internet of Things.

“Our most immediate applications are in agricultural settings, trying to create closed-loop controls. First for watering, but eventually for fertilization and treatment: sensing nitrates, nitrogen, phosphorous, potassium. This could help us understand how to limit run off and other effects,” said Pannuto, senior author on the study titled “Soil Power? Can Microbial Fuel Cells Power Non-Trivial Sensors?”

In biology, symmetry is typically the rule rather than the exception. Our bodies have left and right halves, starfish radiate from a central point and even trees, though not largely symmetrical, still produce symmetrical flowers. In fact, asymmetry in biology seems quite rare by comparison.

Does this mean that evolution has a preference for symmetry? In a new study, an international group of researchers, led by Iain Johnston, a professor in the Department of Mathematics at the University of Bergen in Norway, says it does.

Which, to me, sounds both unimaginably complex and sublimely simple.

Sort of like, perhaps, like our brains.

Building chips with analogs of biological neurons and dendrites and neural networks like our brains is also key to the massive efficiency gains Rain Neuromorphics is claiming: 1,000 times more efficient than existing digital chips from companies like Nvidia.