https://www.stitcher.com/podcast/ctr-network/aging-greatfull…e/53449222
Category: bioengineering – Page 188
CRISPR Isn’t Just for Gene Editing Anymore
A scientist cuts a DNA fragment under UV light for DNA sequencing. Image: AP Five years ago, when researchers first discovered that bacterial immune systems could be hijacked to edit DNA in living creatures, it was big news. The technology, called CRISPR, allowed scientists to more easily than ever cut and paste all those As, Cs, Ts, and Gs that make up the base pairs of DNA and encode the world’s living things. With CRISPR, scientists could use genetic engineering to tackle problems from disease to famine. But gene editing with CRISPR is so 2017. Recently, scientists have begun exploring n…
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Creating designer babies with CRISPR will soon be possible
Summary: Designer babies have recently become possible, as new techniques have gained credibility from serious scientists. Here’s how they can do it. [This article first appeared on LongevityFacts. Author: Brady Hartman. ]
On Feb 8, the AHA named “Fixing a gene mutation in human embryos” as among the “top advances in heart disease and stroke research” of the past year. They joined a chorus of voices heralding this as a research breakthrough.
The announcement brought attention to the fact that US scientists have recently demonstrated the plausibility of using gene editing to make designer babies.
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Engineers use natural protein as nanoshuttle for anti-cancer vaccines
Cancer fighting nanovaccines have shown significant promise, but clinical application has been hampered by complications in large-scale manufacturing, quality control, and safety. Biomedical engineers at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) developed a new technology that enables nanovaccines to bind to the albumin protein naturally present in the body. The albumin protein then delivers these nanocomplexes to the lymph nodes, resulting in potent immune activation against multiple tumor types in mouse cancer models. The use of natural albumin as a universal vaccine shuttle is a significant step towards the application of cancer nanovaccine immunotherapy in humans.
Nanovaccines that work to mount an immune response against a tumor basically consist of two components: the part that delivers the vaccine to the correct site, the lymph nodes, where immune system activation happens; and the part that activates the immune cells to expand and specifically target the tumor.
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Revolutionary stealth virus holds promise for cancer therapy
Researchers solved a problem that has been holding back the use of viral vectors for cancer therapy. They re-engineered viruses with a novel stealth technique that enables them to be used to treat cancer.
Up until now, viral vectors couldn’t be used widely in cancer therapy. Researchers just announced that they re-engineered an adenovirus with a novel stealth technique that enables it to be used to fight tumors. [This article first appeared on the website LongevityFacts.com. Author: Brady Hartman. ]
Viral vectors are well-developed tools used by scientists to deliver genetic material into cells. Unfortunately, they haven’t worked well to treat cancer until a group of researchers in Switzerland re-engineered them to enable them to be used in cancer therapy.
Researchers from the University of Zurich have re-engineered an adenovirus for use in cancer therapy. To achieve this, scientists developed a new protein shield that hides the virus and protects it from being eliminated by the body. Moreover, adapters on the surface of the virus enable the reconstructed virus to target and infect tumor cells.
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