This delayed outflow of material is traveling at 50% of light speed—far faster than typical TDEs.
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by macroscopic features such as cortical atrophy, narrowing of the gyri, widening of the sulci, and enlargement of the ventricles. At the cellular level, the pathological characteristics include the extracellular aggregation of β-amyloid (Aβ) forming senile plaques, and the intracellular accumulation of hyperphosphorylated tau proteins forming neurofibrillary tangles. AD leads to the progressive decline of cognitive, behavioral, and social abilities, with no effective treatment available currently. The pathophysiology of AD is complex, involving mechanisms such as immune dysregulation and lipid metabolism alterations. Immune cells, such as microglia, can identify and clear pathological aggregates like Aβ early in the disease.
Robert Zubrin quite literally wrote the book on why humanity should go to Mars—so why has the renowned aerospace engineer soured on Elon Musk, the billionaire entrepreneur leading the charge?
In an interview, the 73-year-old founder of the Mars Society delivered a blistering critique, accusing the world’s richest person of undermining the mission through divisive politics and a bleak vision of the Red Planet as an escape from Earth rather than a journey of hope.
“On one level, he’s absolutely instrumental in opening up this opportunity to get humans to Mars, both through the development of Starship and also the inspiration that has caused,” Zubrin told AFP, referring to Musk’s prototype rocket.
Thanks to 7T fMRI, researchers from Paris Brain Institute and NeuroSpin, the CEA’s neuroimaging center, are exploring the neural substrate of visual imagery at very high resolution for the first time. Their results, published in Cortex, pave the way for a better understanding of this fascinating cognitive ability, which some of us entirely lack.
Visual imagery—the ability to mentally summon the image of a landscape, a person, or an object that is not directly observable—varies greatly in intensity from one individual to another. Some people can recall a detailed city map and walk through each street as if watching a movie. Thinking of a loved one, others may barely make out their silhouette and hair color.
Interestingly, about 4% of the population seems completely unable to visualize a scene on demand: this is known as aphantasia, a cognitive peculiarity known for over a century but only recently studied by scientists.
The background
Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to separate strands, heating the DNA to over 150 degrees Fahrenheit, a temperature a cell would never naturally reach. By contrast, in a living cell DNA lives in a very crowded environment, and special proteins attach to DNA to mechanically unwind the double helix and then pry it apart.
A lung cancer patient at UCLH is the first to receive a novel cancer vaccine designed to prime the immune system to recognise and fight cancer cells.
UNSW and NeuRA researchers have created an effective therapy for chronic pain that reduces pain intensity by focusing on emotional regulation.
Landauer’s principle connects entropy and energy dissipation in non-equilibrium processes. An experiment now uses this principle to measure entropy production in a Bose gas to resolve contributions from correlations and dissipation.
We know dinosaurs were around 99 million years ago, but now new research has identified a kind of parasitic wasp that was flying around back then (and which has a strange way of catching its prey).
The species now called Sirenobethylus charybdis had a bizarre mechanism that worked like a Venus flytrap which caught the prey, and then the wasps impregnated them with their eggs, researchers noted in the journal BMC Biology.
The Goldman-Hodgkin-Katz model has long guided transport analysis in nanopores and ion channels. This paper (with a companion paper in Physical Review Letters) revisits the model, showing that its constant electric field assumption leads to inconsistencies. A new self-consistent theory, inspired by reverse electrodialysis, offers a unified framework for ion transport.#AdvancingField #BiophysicsSpotlight