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Scientists Investigated People With Insomnia. A Health Risk Pattern Emerged

The researchers identified that across several studies, with more than 1.3 million participants involved, those with insomnia had a 26 percent higher risk of having a stroke. They also found that those people were 28 percent more likely to be hospitalized for any admission reason. Other conditions associated with insomnia included dementia, depression, and suicidal behavior.

When it comes to the association between insomnia and stroke, while research has not yet determined a causal link, Muench said that some theories point toward blood pressure as the potential reason.

“People with insomnia are more likely to develop high blood pressure, but this may be because insomnia and high blood pressure often share the same risk factors, such as stress and lifestyle factors,” she said. “High blood pressure is a risk factor for stroke that people can seek treatment for.”

Superheavy-element compound reveals weaker-than-expected bond due to relativistic effects

An international collaboration led by a research group from GSI/FAIR in Darmstadt, Germany, has achieved the first measurement of the chemical stability of a superheavy element compound.

The focus was on the hexacarbonyl complex Sg(CO)₆ of seaborgium (Sg, element 106). The result: The bond between the seaborgium atom and a carbonyl ligand is weaker than expected based on its position in the periodic table. Relativistic effects are the cause.

The results are published in the journal Nature.

Jonah Sachs on Winning the Story Wars: Storytelling is our neglected secret weapon

2022, months before ChatGPT turned everyone into a prompt engineer, I spent two hours with Jonah Sachs on a question that now feels urgent: who gets to tell the story?

Jonah has earned the right to an opinion. His film for Amnesty International on blood diamonds was delivered to every member of Congress and helped pass the Clean Diamond Act. The Story of Stuff, which he helped create, reached over 60 million people. He didn’t win those fights with spreadsheets. He won them with #storytelling.

His line has stayed with me ever since: storytelling is the neglected secret weapon we all have.

Here’s what bothers me today. Machines now produce stories by the billion. So is that weapon being handed over to #AI, or is it becoming the one thing that still separates us from the noise?

We went deep on the hero’s journey, the five markers of a great story, what’s broken in our current human story, GPT-3 and two very different Turing Tests, and what Jonah calls the poison and the cure of story. Then he brought up a Buddhist test of suffering that I haven’t been able to shake.

If you work in #marketing, lead people, or care about #socialchange, this one is worth your time. Four years later, it lands harder than it did the day we recorded it.

On the Business Strategies of Platform Biotech Companies

Platform biotech companies face a different strategic landscape relative to single-asset biotechs. Here’s my short educational writeup on the fundamentals of the platform biotech business approach.


Investors may sometimes favor platform biotech companies, though usually only when markets are strong. While opinion tends to swing with the markets, there are certain real advantages to platforms. Particularly, investors find attractive structures with more routes to a very large return outcome, which platforms can offer.

A single-asset company typically will generate a return if it shows a clinical success (often successful phase 2 or even phase 3 clinical trial data) with its sole program and is acquired. By contrast, platform companies are not always killed by a single program failure. So, platforms provide more shots on goal in a sense. That said, if the core platform (e.g. delivery system) fails in humans, the entire company will die [1]. Because of this, it is still critical that the platform company’s first asset program goes well.

Platforms feature routes to preclinical revenue which are much more difficult to achieve for assets. Pharma companies will pay for access to enabling platform technology even when only preclinical data are available. Programs by Dyno Therapeutics (AAVs) [2] and Evox Therapeutics (exosomes) [3] represent examples of the phenomenon. This provides third-party validation and non-dilutive capital before the clinical data, which can support the company during the otherwise most challenging period in a biotech’s lifetime.

Robotok: Mining Internet Videos for Dexterous Robot Learning

What if robots could learn dexterous skills by watching videos on the internet?

Teaching robots to manipulate objects is challenging because collecting training data is expensive, time-consuming, and difficult to scale across different tasks and environments. Humans, on the other hand, demonstrate countless everyday skills in videos uploaded online. The challenge is finding the right demonstrations that can help a robot learn how to perform a specific action.

A new system called RoboTok tackles this problem by turning internet videos into a searchable resource for robot learning. Given a reference video of a person performing a manipulation task, RoboTok searches for other videos showing similar hand movements and interactions with objects. Rather than relying mainly on visual similarities, it analyzes the motion trajectories of the hands in three-dimensional space, using a representation centered on the person performing the action.

This approach allows the system to recognize similar manipulation behaviors even when videos differ in camera angles, backgrounds, visual appearances, or when parts of the person’s body are obscured. Because the motion representation is compact, RoboTok can also index and search large collections of online videos efficiently.

The researchers evaluated the system using video-retrieval benchmarks and real-world robot experiments. Their results showed that RoboTok retrieved more relevant demonstrations than existing approaches and helped robots perform manipulation tasks more successfully. In real-world tests, RoboTok-guided robot policies achieved an average improvement of 42.2 percentage points in task success rates compared with the strongest baseline for each task.

The broader implication is significant: the internet could become a vast, continuously growing source of training data for robots. Instead of relying exclusively on costly, specially collected robot demonstrations, researchers could extract useful manipulation examples from videos of humans performing everyday tasks.

RoboTok does not mean robots can automatically master every skill simply by watching videos. They still need suitable learning methods and robot-specific training. But by making human demonstrations easier to find and reuse, this approach offers a promising path toward more scalable robot learning and more dexterous machines.

#ArtificialIntelligence #robotics #ImitationLearning #DexterousManipulation.

Astronomers Have Detected A Mysterious Signal Coming From Empty Space. Nobody Knows What It Is

In the southern constellation of Fornax lies a tiny patch of sky just like any other. Your eyes may have brushed past it a hundred times without a thought.

Yet this otherwise unremarkable speck of the cosmos is among the most well-cataloged in the sky. The Hubble Space Telescope stared at it for more than 270 hours to obtain its famous Ultra Deep Field (HUDF) – and contained therein are nearly 10,000 galaxies extending billions of light-years into the Universe.

When the James Webb Space Telescope (JWST) launched, it was only natural that its golden mirrors would turn to the same region of space, using its vastly more sensitive infrared capabilities to find what Hubble may have missed.

Common leukemia mutation derails protein positioning during cell division, study reveals

Experts from the University of Nottingham have discovered how a common genetic mutation disrupts the positioning of a key protein during cell division, revealing a new mechanism behind acute myeloid leukemia and a potential avenue for future treatment.

Acute myeloid leukemia (AML) is an aggressive blood cancer that disrupts the production of healthy blood cells. Around one-third of patients carry a mutation in a gene called NPM1, which causes its protein to accumulate in the wrong part of the cell and plays a key role in driving the disease.

Until now, research has largely focused on how the mutated protein moves between the cell’s nucleus and the surrounding cytoplasm. But a new study, led by Dr. Daniel Booth and Dr. Claire Seedhouse at the University of Nottingham’s School of Medicine, reveals that what happens during cell division itself is also critical.

Linus Torvalds says AI is a gateway drug for coding

Linus Torvalds is using AI to develop Linux kernel code now https://www.zdnet.com/innovation/linus-torvalds-uses-ai-to-w…nel-patch/

Linux creator Linus Torvalds says AI is like a “gateway drug”


Linus Torvalds AI stance has softened as he says tools boost productivity but still create false bug reports. Read what his comments reveal.

I Tested AI Cloning… and It’s Way Worse Than You Think!

I used AI to reverse engineer real binaries, understand how they work, and then clone their functionality into brand-new applications. In this video I show the full process — what the AI can actually figure out, where it falls short, and how far you can push the technique of turning an existing binary into something new.

This is the practical side of AI-assisted reverse engineering, not theory.

What you’ll see:

How AI helps tear apart and understand binaries.
Extracting logic, behavior, and structure.
Cloning that functionality into a clean new application.
Real examples of what works and what still needs a human engineer.
The limits, risks, and surprising capabilities of current tools.

If you’ve ever wondered how far AI can go in reverse-engineering and recreating software from binaries, this is the deep dive.

For a free download of Task Manager TMOG, visit: https://tmog.org