It sounds like a nightmare. The idea of anesthesia wearing off in the middle of a procedure and suddenly getting an eyeful of your own insides. Thankfully, anesthesiologists are generally very good at their jobs. When they put you under, you’re not supposed to be awake or aware of anything. But according to new research published in Nature, that doesn’t necessarily mean every part of your brain is shut down.
Scientists have assumed that general anesthesia shuts down your higher-level brain activity, the parts associated with consciousness. But a team of researchers from Baylor College of Medicine found that even while patients were fully anesthetized, individual neurons in the hippocampus were still up and running, doing all of the memorization and learning stuff that the hippocampus is supposed to do.
Using high-density Neuropixels probes implanted in seven epilepsy patients undergoing surgery, researchers were able to monitor hundreds of individual neurons while patients were unconscious. They were played a series of sounds through headphones while under anesthesia and watched how the brain responded. The sounds included podcasts, stories, and different bits of human speech.
