More than half of young adults with type 2 diabetes put their disease into remission after six months on a combined low-calorie diet and supervised exercise program, according to an international trial led by two Nominated Principal Investigators, Dr. Kaberi Dasgupta, Senior Scientist in the Metabolic Disorders and Complications Program and the Centre for Outcomes Research and Evaluation at the Research Institute of the McGill University Health Centre (The Institute) and Professor Tom Yates of the University of Leicester, in a Canada-UK collaboration that marked the 100th anniversary of the discovery of insulin.

The RESET for Remission study was recently published in The Lancet Regional Health – Americas and presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Milan. Of the 50 young adults with type 2 diabetes who randomized to the intensive diet and exercise program, 27 (54%) reached remission, compared with just 2 of 46 (4%) who received usual care. Remission means blood sugar drops below the level used to diagnose diabetes, with no diabetes medication for at least 12 weeks. Importantly, they also had other key health benefits.