The biggest thing in this is Sinclair mentioning A.I. turned 160 years worth of drug cocktail discovery into 2 months.

An AI designed a drug for a deadly lung disease, and six different aging clocks say it made people biologically younger. Rentosertib, from Insilico Medicine, was built to treat idiopathic pulmonary fibrosis. But when researchers ran patients’ blood through six proteomic aging clocks from six separate labs, all six read the treated patients as younger, by roughly 3 to 4 years at the peak.

We break down how AI found both the target and the molecule, what the new Nature Biotechnology paper actually shows (and what the hype got wrong), and why Insilico’s \.