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AI designs functional enzyme components that could help expand drug discovery

New active ingredients for drugs to treat infections, cancer or other serious diseases are often based on substances originally discovered in microorganisms, plants or other living organisms. Producing or improving such active ingredients in a targeted manner using microorganisms is often challenging because the underlying biological processes are extremely complex.

Researchers at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have now shown that artificial intelligence can help with this task. Using AI, they developed novel protein building blocks for biological production systems. The researchers published their findings in the journal Nature Communications.

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