Researchers have uncovered a previously unknown gene that causes resistance to a leading blood cancer drug, as well as several genes that accelerate lymphoma growth, using a powerful new CRISPR activation library.

Traditional CRISPR is a genetic engineering tool that allows scientists to easily delete specific genes in an organism’s DNA and assess their role and importance. It has become a cornerstone technology in cancer research.

A newer frontier is CRISPR activation, a technique that enables the activation of specific genes. It offers valuable insights into the roles of certain genes in cancer and other genetic disorders.