ABT-263 also increased the activity of genes involved in rebuilding damaged tissue. These included genes associated with collagen production and the formation of new blood vessels.

Collagen is a structural protein that provides strength and support to skin and other tissues. New blood vessel growth is equally important because healing tissue needs a steady supply of oxygen and nutrients as it rebuilds itself.

Together, these changes suggest that ABT-263 did more than simply remove damaged cells. The treatment also appeared to create conditions that helped aging skin mount a stronger regenerative response.