An AI assistant helped University of Colorado Boulder researchers solve a mathematical problem that had challenged their lab for a year and a half, though it made subtle errors along the way. The breakthrough could improve how scientists study nanoparticles—tiny particles about 1,000 times thinner than a human hair—but it reveals both the promise and limitations of AI as a scientific research partner.

The new study, published in the Journal of Fluid Mechanics, details the solution to a decades-old fluid mechanics problem and explains how researchers combined AI with human expertise to reach the answer.

The research was led by Ankur Gupta, an assistant professor of chemical and biological engineering, and his graduate student, Arkava Ganguly, who spent a year and a half working on the problem. With help from Anthropic’s Claude AI, they discovered that changing a nanoparticle’s shape, such as by stretching it from a circle to a football shape, changes how fast it moves in an electric field, while adding finer features, such as bumps or ripples, does not.