AutoimmuneDiseases affect nearly 50 million Americans, and 4 out of 5 patients are women.
https://doi.org/10.1172/JCI198291 In this Research Letter, Howard Y. Chang & team show novel autoantibodies target hotspots on the XIST ribonucleoprotein complex in female-biased autoimmune diseases.
1Department of Dermatology and.
2Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
3RNA Medicine Program, Stanford University, Stanford, California, USA.
4Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.