Online now: Body-wide multi-omic counteraction of aging with GLP-1R agonism: (Cell Metabolism 37, 2362–2380.e1–e8; December 2, 2025)
Online now: (Cell Metabolism 37, 2362–2380.e1–e8; December 2, 2025)
Following publication, Steve Horvath and colleagues at the Clock Foundation alerted us to a platemap error in the DNA methylation (DNAm) data. Our investigation pinpointed the potential source of this error. We provided samples on 96-well plates in a row-wise orientation instead of the column-wise orientation specified in the Clock Foundation’s protocol. Subsequently, incorrect assignment of metadata for 36 samples (out of 459) that contributed data to the paper likely occurred during the transposition and rearrangement of a subset of samples on two incompletely filled plates prior to the assay. Working with Clock Foundation colleagues, we have corrected the metadata for 33 samples and discarded 3 samples for which we could not retrieve the metadata with total certainty.
This error impacted DNAm data for the following tissues:
