https://doi.org/10.1172/JCI195772 Sundeep Khosla & team compare the senescence phenotype of mesenchymal versus immune cells from murine bone and bone marrow, revealing important differences between them.

The figure shows mesenchymal cells exhibit higher absolute levels of senescence signatures than immune cells.

Address correspondence to: Madison L. Doolittle, Center for Regenerative Medicine and Skeletal Development, UConn Health, 263 Farmington Avenue, Farmington, Connecticut 6,030, USA. Phone: 860.679.1757; Email: [email protected]. Or to: Sundeep Khosla, Guggenheim 7, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, Minnesota 55,905, USA. Phone: 507.255.6663; Email: [email protected].