Zhao & colleagues found how a protective protein, USP10, helps limit excessive inflammation after a heart attack, which may open new avenues for treating cardiac injury. Learn more at.

BACKGROUND: Myocardial infarction (MI) results in 3 distinct regions within the left ventricle:

The infarct zone, the border zone (BZ), and the remote zone. A major focus of MI research.

Is investigating the intrinsic mechanisms in the BZ to alleviate myocardial injury.

USP10 (ubiquitin-specific peptidase 10) expression is reduced in BZ cardiomyocytes.