RCT: Among adults with mTBI, targeted multidomain interventions and usual care behavioral management resulted in similar improvements in overall symptom severity and patient-perceived recovery over 4 weeks.

Question Is a targeted multidomain (T-MD) intervention more effective than a standardized behavioral management intervention in adults with mild traumatic brain injury (mTBI)?

Findings In this randomized clinical trial of 162 patients, both the T-MD and behavioral management groups experienced similar improvements in mTBI symptom severity and perceived improvement in primary outcomes over 4 weeks.

Meaning The findings suggest that both T-MD and behavioral management are effective for improving global mTBI symptoms.