Gou Young Koh & team establish ERG and Fli1 as core transcriptional regulators of lymphatic identity, integrity, and function, using human cells and mouse models:
The figure shows stasis of mesenteric lymphatic drainage for a tracer (red) in Prox1-GFP-mice lacking Erg/Fli1 specifically in lymphatic endothelial cells compared with Prox1-GFP-WT mice; with Prox1-GFP marking lymphatic structures (green).
1Center for Vascular Research, Institute for Basic Science, Daejeon, South Korea.
2Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.
Address correspondence to: Hyuek Jong Lee or Gou Young Koh, Center for Vascular Research, Institute for Basic Science, Daejeon 34,141, South Korea. Email: [email protected] (HJL); [email protected] (GYK).