Here, Miguel Verbitsky & team analyze urine from 325 participants in the Randomized Intervention for Children with Vesicoureteral Reflux study (RIVUR study), revealing genetic variations influence bacterial composition of urine in children with recurrent urinary infections and vesicoureteral reflux:
The image shows cytokeratin 5 and smooth muscle actin labeling after UTI in mouse bladder, which increases expression of Cxcl12 and Cxcr4.
3Department of Dermatology; and.
4Center for Precision Medicine and Genomics, Columbia University, New York, New York, USA.
5Department of Neurology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.