Yanchang Wang and colleagues (Florida State University) show that in yeast, polo-like kinase Cdc5 promotes the phosphorylation of SUMO protease Ulp2, reducing its affinity for SUMO chains and thereby facilitating polySUMOylation.
Genetics CellCycle
1Infectious Diseases Division, Department of Medicine and.
2Division of Plastic and Reconstructive Surgery, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
3Department of Mathematics, Dartmouth College, Hanover, New Hampshire, USA.