New preprint reports 17-month lifespan extension in mice with some living nearly 5 years. The intervention targets immune aging through CD4+ T cells and is expected to enter human trials in 2026.
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A new preprint by Lanna et al. reports one of the largest lifespan extensions ever seen in mice; approximately 17 months, with some mice living close to 5 years. The study focuses on metabolically reprogramming CD4+ T cells from aged mice using a peptide called DOS, which enables these cells to produce \.