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Real-time imaging reveals new mechanisms for pancreatic ductal establishment and remodeling

Abigail Laura Jackson, Silja Heilmann, Pia Nyeng (Roskilde Universitet – RUC) and colleagues use a new apical polarity reporter mouse & high-resolution live imaging to demonstrate that pancreatic tubulogenesis is driven by dynamic transformations of existing lumens, which establish and remodel the pancreatic duct.


Jackson and Heilmann et al. use a new apical polarity reporter mouse and high-resolution live imaging to demonstrate that pancreatic tubulogenesis is drive.

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