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How does the small molecule NVP-BHG712 protect against pulmonary fibrosis in mice?

Mohit Kapoor & team identify EphB4 receptor as a crucial mediator of pulmonary fibrosis that regulates genes involved in ECM organization, ER cargo concentration and protein trafficking in fibroblasts.


4Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.

5Department of Biostatistics, University Health Network, Toronto, Ontario, Canada.

6Dalla Lana School of Public Health and Department of Statistical Sciences, University of Toronto, Toronto, Ontario, Canada.

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