A previously unrecognized estrogen-dependent signaling pathway in the gut regulates visceral pain sensitivity in mice, according to a new Science study. The findings provide a pathway toward targeted therapeutic strategies.

Learn more in a new Science Perspective.

Estrogen tunes a cross-talk between hormone-secreting cells in the mouse gut to regulate visceral pain.

Amélie Joly and Irene Miguel-Aliaga Authors Info & Affiliations

Science

Vol 390, Issue 6779