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Do ICIs Have Long-Term Survival Benefit?

A cross‑sectional analysis found that few registration trials assessing immune checkpoint inhibitors (ICIs) cancer therapies report long-term overall survival data. Among nearly 90 FDA-approved ICIs indications in the metastatic setting, less than one third of trials had overall survival data at 3 years, and even fewer (about 11%) reported overall survival data at 5 years.


Most registration trials for ICI cancer therapies don’t report long term overall survival data, a cross-sectional analysis finds.

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