Using a new strategy for quantifying mitochondrial DNA, Mark L. Hepokoski & team show the release of mtDNA from the kidney directly contributes to interleukin-6 release during sepsis associated AKI.
1VA San Diego Healthcare System, San Diego, California, USA.
2Division of Pulmonary and Critical Care and Sleep Medicine, UCSD, La Jolla, California, USA.
3Department of Critical Care Medicine, Yantai Yuhuangding Hospital, Affiliated with Medical College of Qingdao University, Yantai, Shandong, China.