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A bacterial toxin disarms gut defenses against inflammation

A toxin-secreting gut bacterium may fuel ulcerative colitis by killing protective immune cells that maintain intestinal homeostasis, according to a new study in Science. The findings suggest potential for new treatment strategies.

Learn more in a new Science Perspective.


Macrophage-toxic bacteria from patients with ulcerative colitis worsen gut inflammation in mice.

Sonia Modilevsky and Shai Bel Authors Info & Affiliations

Science

Vol 390, Issue 6775

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