Dual‐Lineage Chondrocyte‐Like Cells in the Nucleus Pulposus of Aging Intervertebral Discs Are Accelerated by Hedgehog Signaling Inactivation
During intervertebral disc degeneration, notochord-derived nucleus pulposus cells progressively transdifferentiate into Krt19+ chondrocyte-like cells (CLCs) and Krt19− CLCs, which are eventually repl…
