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Nascent RNA profiling uncovers molecular drivers of cellular differentiation

Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have documented their use of a new RNA sequencing technology to uncover molecular drivers of cellular differentiation that could lead to better regenerative therapies.

In addition to being used in the lab, the technique, Rapid Precision Run-On Sequencing (rPRO-seq), has the potential to help doctors understand patients’ disease states and response to treatment in real time.

The findings appear in two published articles in Molecular Cell.

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