Polymer-coated nanoparticles loaded with therapeutic drugs show significant promise for cancer treatment, including ovarian cancer. These particles can be targeted directly to tumors, where they release their payload while avoiding many of the side effects of traditional chemotherapy.
Over the past decade, MIT Institute Professor Paula Hammond and her students have created a variety of these particles using a technique known as layer-by-layer assembly. They’ve shown that the particles can effectively combat cancer in mouse studies.
To help move these nanoparticles closer to human use, the researchers have now come up with a manufacturing technique that allows them to generate larger quantities of the particles, in a fraction of the time.