Summary: The dural sinuses and skull bone marrow serve as key communication hubs between the brain’s central immune system and the body’s peripheral immune system. These regions may act as “traffic lights,” allowing immune signals to flow between the brain and body, challenging the traditional view of the blood-brain barrier as an absolute divide.
Researchers found inflammatory activity in these areas correlates with inflammation in both the brain and body, offering new insights into conditions like depression. This discovery could pave the way for innovative treatments targeting these hubs to address immune-related conditions more precisely.
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