Summary: A new study has identified a brain protein, vesicular nucleotide transporter (Vnut), as essential for regulating mood and motivation in mice. When Vnut was removed from brain cells called astrocytes, the mice displayed higher anxiety, depression-like behavior, and decreased motivation, especially in females.
This effect was linked to reduced dopamine, a key molecule for motivation and positive mood. These findings suggest Vnut plays a vital role in dopamine regulation, with potential implications for understanding mood disorders.
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