Recent research challenges the long-standing understanding of the end-replication problem in DNA, revealing two distinct issues rather than one.
Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres that protect the ends of chromosomes should have been growing shorter with each round of replication, a phenomenon known as the end-replication problem.
Telomerase: A Solution Emerges
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