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Nov 23, 2021

SARS-CoV-2 gene content and COVID-19 mutation impact

Posted by in categories: biological, biotech/medical, genetics

The SARS-CoV-2 gene set remains unresolved, hindering dissection of COVID-19 biology. Comparing 44 Sarbecovirus genomes provides a high-confidence protein-coding gene set. The study characterizes protein-level and nucleotide-level evolutionary constraints, and prioritizes functional mutations from the ongoing COVID-19 pandemic.

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