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Aug 5, 2021

Synthetic extracellular matrices with tailored adhesiveness and degradability support lumen formation during angiogenic sprouting

Posted by in categories: bioengineering, biotech/medical

Current tissue engineering strategies lack materials that promote angiogenesis. Here the authors develop a microfluidic in vitro model in which chemokine-guided endothelial cell sprouting into a tunable hydrogel is followed by the formation of perfusable lumens to determine the material properties that regulate angiogenesis.

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