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Feb 11, 2021

Mechanochemical bond scission for the activation of drugs

Posted by in categories: biotech/medical, chemistry, nanotechnology

Stimuli-responsive control of drug activation can mitigate issues caused by poor drug selectivity. Now, it has been shown that mechanical force—induced by ultrasound—can be used to activate drugs in three different systems. This approach has enabled the activation of antibiotics or a cytotoxic anticancer agent from synthetic polymers, polyaptamers and nanoparticle assemblies.

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