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May 15, 2020

Vitamin B3 revitalizes energy metabolism in muscle disease

Posted by in categories: biotech/medical, life extension

An international team of scientists, led by University of Helsinki reported that vitamin B3, niacin, has therapeutic effects in progressive muscle disease. Niacin delayed disease progression in patients with mitochondrial myopathy, a progressive disease with no previous curative treatments.

Vitamin B3 forms have recently emerged as potent boosters of energy metabolism in rodents. These vitamins are precursors for NAD+, a molecular switch of metabolism between fasting and growth modes.

As fasting has been shown promote health and longevity in for example mice, a variety of “NAD boosters” are being developed. However, whether actual NAD+ deficiency exists in , and whether NAD+ boosters could have curative effects in patients with degenerative diseases, has remained elusive.

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