For the first time, researchers have mapped the cell nucleus in 3D, revealing the packaging and organization of a cell’s DNA in unprecedented detail.
June 8 (UPI) — The nucleus of the cell is where the action happens, but it’s not easy to analyze the behavior of a massive genome inside an area 50 times smaller than the width of a human hair.
Now, for the first time, researchers have mapped the cell nucleus in 3D, revealing the packaging and organization of a cell’s DNA in unprecedented detail.
Inside each cell is the same massive chain of DNA. But most of the coding lies dormant. The combination of genetic sequences within in the chain that are turned off or on — and expressed via RNA — determines the role and functionality of each cell.
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