Lifeboat Foundation

A cancer therapy that prompts the body’s immune defenses against viruses and bacteria to attack tumors can make patients more vulnerable to heart attack and stroke. A possible explanation for this side effect is that the treatment interferes with immune regulation in the heart’s largest blood vessels, a new study suggests.

Led by researchers at NYU Langone Health and its Perlmutter Cancer Center, the new work focused on a potent class of cancer-fighting drugs called immune checkpoint inhibitors. These medications work by blocking molecules embedded on the surface of cells—immune checkpoints—which normally serve as “brake pedals” that prevent excess immune activity, or inflammation. Some tumors are known to hijack these checkpoints to weaken the body’s defenses, so by blocking the checkpoints, the treatments enable the immune system to kill tumor cells.

However, this treatment type may also trigger damaging levels of inflammation in the heart, brain, stomach, and other organs, the researchers say. For example, past studies have shown that about 10% of those with atherosclerosis, the buildup of hardened fatty deposits (plaques) within artery walls, have a heart attack or stroke following cancer treatment. However, the specific mechanisms behind this issue had until now remained unclear.

Cure-Focused Diabetes Research — Michael Burton & Prof. Matthias von Herrath — Diabetes Research Institute Foundation.

Michael J. Burton is the CEO of the Diabetes Research Institute Foundation (https://diabetesresearch.org/), a philanthropic organization which funds the Diabetes Research Institute, one of the largest and most comprehensive research centers dedicated to curing diabetes.

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Bas Mettes astounded the community with his 12th Houdini test.

Elon Musk’s ‘fully autonomous’ cars will, like other robotaxi vehicles, rely on remote human pilots.

Summary: Researchers identified specific plant compounds that provide antioxidant and neuroprotective effects, contributing to brain health beyond basic nutrition. By analyzing plant-based foods like lemon balm, sage, and elderberry, scientists linked compounds such as phenolics and terpenes to benefits like reducing oxidative stress and scavenging harmful reactive species.

Quercetin-rich foods, such as Queen Garnet plum and clove, showed strong potential to prevent neuron-like cell damage. This study sheds light on how plant-based diets and supplements could support brain health and manage neuroinflammation-related conditions.

Unveiling Quantum Scars: A Window into Chaos in Graphene Quantum Dots.

In the realm of quantum physics, certain phenomena challenge our understanding of chaos and order.

Patterns in chaos have been proven, in the incredibly tiny quantum realm, by an international team co-led by UC Santa Cruz physicist Jairo Velasco, Jr. In a new paper published on November 27 in Nature, the researchers detail an experiment that confirms a theory first put forth 40 years ago stating that electrons confined in quantum space would move along common paths rather than producing a chaotic jumble of trajectories.

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Researchers have successfully developed a supramolecular fluorophore nanocomposite fabrication technology using nanomaterials and constructed a sustainable solar organic biohydrogen production system.

The research team used the good nanosurface adsorption properties of tannic acid-based metal-polyphenol polymers to control the self-assembly and optical properties of fluorescent dyes while also identifying the photoexcitation and electron transfer mechanisms. Based on these findings, he implemented a solar-based biohydrogen production system using bacteria with hydrogenase enzymes.

The findings are published in the journal Angewandte Chemie International Edition. The joint research was led by Professor Hyojung Cha at the Department of Hydrogen and Renewable Energy, Kyungpook National University and Professor Chiyoung Park at the Department of Energy Science and Engineering, Daegu Gyeongbuk Institute of Science & Technology.

Video games get microscopic in an educational science outreach project.

WASHINGTON — Varda Space Industries secured a $48 million contract from the U.S. Air Force Research Laboratory to test military payloads on the company’s reentry capsules.

A California-based startup focused on in-space manufacturing, Varda Space developed a factory-in-orbit spacecraft — a compact, 120-kilogram satellite engineered to produce high-value materials such as pharmaceuticals in zero-gravity conditions. The materials are returned to Earth in a capsule built with advanced thermal protection materials developed by NASA to withstand reentry.

The four-year deal with AFRL, announced on Nov. 26, leverages Varda’s W-Series reentry capsules as platforms to test payloads at hypersonic speeds. The spacecraft are built on Rocket Lab’s Photon satellite bus.