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A longstanding problem in optics holds that an improved resolution in imaging is offset by a loss in the depth of focus. Now, scientists are joining computation with X-ray imaging as they develop a new and exciting technique to bypass this limitation.

The upcoming Advanced Photon Source Upgrade (APS-U) project at Argonne will put this problem under one of the brightest spotlights imaginable. The upgrade will make the APS, a Department of Energy Office of Science User Facility, 500 times brighter than it is today, further enhancing the capabilities of its X-rays to study the arrangements of atoms and molecules in a wide range of biological and technological materials.

“A whole variety of X-ray imaging experiments ultimately will need something like this as they all push the resolution to finer length scales in the future,” said Chris Jacobsen, an Argonne Distinguished Fellow and professor of physics at Northwestern University. With the Upgrade in place, the APS’s X-rays could allow scientists to study systems like the brain’s full network of synaptic connections, or the entire volume of an integrated circuit down to its finest details.

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Investigators from the Neurodegenerative Diseases Research Group at the University of Extremadura are studying signaling mediated by a pathway known as planar cell polarity (PCP), which regulates the coordinated orientation of cells during organogenesis, the process of organ formation in living organisms. This pathway has been highly conserved on the evolutionary scale, and one of its key functions in vertebrates is the regulation of the coordinated positioning of centrioles/ciliary basal cells inside cells.

This signaling pathway was discovered initially in the fruit fly genus Drosophila, although the majority of the pathway components have been retained in humans. It has likewise been observed that certain pathologies such as hydrocephaly, infertility and some kinds of cancers are associated with defective functioning of this signaling.

Under the auspices of the project EPICENTR within the Spanish national research plan, whose objective is to study the planar polarisation of centrioles in epithelial , the UEx researchers have now published the first results of their investigation in the journal Development. These results are related to the polarised positioning mechanism of centrioles in Drosophila and its correlation with actin.

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NASA offered to give Stephen Curry a tour of its lunar labs in Houston after the NBA superstar expressed doubts on the moon landings.


Three-time NBA champion Stephen Curry on Tuesday signaled that he is willing to take NASA up on its offer to tour its lunar lab in Houston after his pronouncement this week that he does not believe humans ever walked on the Moon.

During the “Winging It” podcast released on Monday, the Golden State Warriors guard asked fellow players Vince Carter and Kent Bazemore whether they believed humans had ever been to the Moon.

The players said they did not, to which two-time MVP Curry said: “They’re gonna come get us. I don’t think so either.”