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Seneca Valley virus sounds like the last bug you’d want to catch, but it could be the next breakthrough cancer therapy. Now, scientists at the Okinawa Institute of Science and Technology (OIST) and the University of Otago have described exactly how the virus interacts with tumors—and why it leaves healthy tissues alone.

The study, published in the Proceedings of the National Academy of Sciences on October 29, 2018, provides the first detailed images of how the complex Seneca Valley forms with its preferred receptor. The researchers used cryo-electron microscopy to capture images of over 7000 particles and rendered the structure in high resolution. They predict their results will help scientists develop the virus, and other viral drug candidates, for clinical use.

“If you have a virus that targets cancer cells and nothing else, that’s the ultimate cancer fighting tool,” said Prof. Matthias Wolf, principal investigator of the Molecular Cryo-Electron Microscopy Unit at OIST and co-senior author of the study. “I expect this study will lead to efforts to design viruses for .”

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And how to build a time machine.


The concept of time travel has always captured the imagination of physicists and laypersons alike. But is it really possible? Of course it is. We’re doing it right now, aren’t we? We are all traveling into the future one second at a time.

But that was not what you were thinking. Can we travel much further into the future? Absolutely.

If we could travel close to the speed of light, or in the proximity of a black hole, time would slow down enabling us to travel arbitrarily far into the future. The really interesting question is whether we can travel back into the past.

The innovators and discoverers of tomorrow took centre stage in Chesterfield Inlet when Victor Sammurtok School (VSS) hosted its Elementary Science Fair on Dec. 4. Local fairs in schools across the region led up to the Kivalliq Science Educators’ Community’s (KSEC) Kivalliq Regional Science Fair, where students were vying for the right to represent the…

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To tackle widespread scientific misconduct, the Chinese government has expanded its controversial social credit system to include infractions made by research scientists. The plan could scare some scientists straight—but the potential for abuse is very real.

“Researchers in China who commit scientific misconduct could soon be prevented from getting a bank loan, running a company or applying for a public-service job,” reports science writer David Cyranoski at Nature News.

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