Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog – Page 9622

Graeme Ross: “Once again the over-riding need to measure the immeasurable raises it‘s ugly head. Statistics are proof of ignorance. Numbers are not knowledge. It has been mooted that we are a mental construct that incorporates multiple persona in our subconscious and semi-conscious mind. Find the theory for yourself. I wont quote what you can find yourselves. If we are a construct, ever-changing, ever-evolving in complexity and moment-to-moment inner focus, and if, as it has been mooted, we have constant and endless conversation with these ever-changing inner mental persona, then it follows that without capturing that process in mid-flight (as it were) we can‘t deduce the reasoning that results from these conversations. Therefore we are not able to quantify these processes in any way at all. It is ephemeral. Thought takes place in the interval between knowing and asking. Trying to build a machine that will think would take far more resources than mankind will ever possess.”

Abstract: This paper outlines the Independent Core Observer Model (ICOM) Theory of Consciousness defined as a computational model of consciousness that is objectively measurable and an abstraction produced by a mathematical model where the subjective experience of the system is only subjective from the point of view of the abstracted logical core or conscious part of the system where it is modeled in the core of the system objectively. Given the lack of agreed-upon definitions around consciousness theory, this paper sets precise definitions designed to act as a foundation or baseline for additional theoretical and real-world research in ICOM based AGI (Artificial General Intelligence) systems that can have qualia measured objectively.

Published via Conference/Review Board: ICIST 2018 – International Conference on Information Science and Technology – China – April 20-22nd. (IEEE conference) [release pending] and https://www.itm-conferences.org/

Introduction The Independent Core Observer Model Theory of Consciousness is partially built on the Computational Theory of Mind (Rescorla 2016) where one of the core issues with research into artificial general intelligence (AGI) is the absence of objective measurements and data as they are ambiguous given the lack of agreed-upon objective measures of consciousness (Seth 2007). To continue serious work in the field we need to be able to measure consciousness in a consistent way that is not presupposing different theories of the nature of consciousness (Dienes and Seth 2012) and further not dependent on various ways of measuring biological systems (Dienes and Seth 2010) but focused on the elements of a conscious mind in the abstract. With the more nebulous Computational Theory of Mind, research into the human brain does show some underlying evidence.

Continue reading “The Independent Core Observer Model Computational Theory of Consciousness and the Mathematical model for Subjective Experience” | >

Chaos in bodily regulation can optimize our immune system according to a recent discovery made by researchers at the University of Copenhagen’s Niels Bohr Institute. The discovery may prove to be of great significance for avoiding serious diseases such as cancer and diabetes.

Wide gaps exist in our understanding of how the immune system works and how we might avoid diseases such as cancer and diabetes. Now, two researchers at the University of Copenhagen’s Niels Bohr Institute have made a discovery that could prove to be an important piece of the puzzle. PhD Mathias Heltberg and Professor Mogens Høgh Jensen have found an entirely new mechanism in the way that bodily cells regulate themselves — through chaos.

The researchers investigated how a particular protein produced within cells, NF-kB, stimulates genes. Among other things, this particular protein is vital for maintaining the body’s immune defense system and thereby, the body’s ability to combat disease. The concentration of NF-kB fluctuates over time, and these swings impact the genes and subsequently, the condition of cells.

Read more

Microbes are often seen as pathogens that cause disease and antibiotics have been used successfully to combat these foreign invaders. In reality, the picture is more complex. Most of the time we live in harmony with our commensal gut microbiota, which is the collection of microorganisms colonizing the healthy gut. Commensal bacteria regulate host biological functions, including skeletal health. Researchers at the Medical University of South Carolina (MUSC) studying osteoimmunology, the interface of the skeletal and immune systems, have examined the impact of disrupting the healthy gut microbiome with antibiotics on post-pubertal skeletal development. Their results, published online on the January 16, 2019 in the American Journal of Pathology, showed that antibiotic disruption of the gut microbiota induced a pro-inflammatory response that led to increased activity of osteoclasts.

“This report introduces antibiotics as a critical exogenous modulator of gut microbiota osteoimmune response during post-pubertal skeletal development,” says Chad M. Novince, D.D.S., Ph.D., assistant professor in both the Colleges of Medicine and Dental Medicine who studies the impact of the microbiome on osteoimmunology and skeletal development. “People have shown that antibiotics perturb the microbiota, but this is the first known study evaluating how that has downstream effects on immune cells that regulate bone cells and the overall skeletal phenotype. This work brings the whole story together.”

The post-pubertal phase of development is a critical window of plasticity that supports the accrual of approximately 40 percent of our peak bone-mass. Recent work by the Novince lab and others has shown that the gut microbiota contributes to skeletal health. To determine the impact of antibiotic perturbation of the gut microbiota in post-pubertal skeletal development, Novince worked with team members at MUSC and treated mice with a cocktail of three antibiotics. In collaboration with microbiome scientist Alexander V. Alekseyenko, Ph.D., associate professor in the Biomedical Informatics Center and founding director of the MUSC Program for Human Microbiome Research, they were able to show that antibiotic treatment led to major alterations in the gut microbiota, resulting in specific changes to large groups of bacteria.

Read more