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The recent clinical trial was only conducted on patients with lymphoma, but the researchers suggested their approach could be potentially used to treat other types of cancer — and that it could improve the efficacy of other immunotherapies, including checkpoint blockade.

“The in situ vaccine approach has broad implications for multiple types of cancer,” said Brody, the study’s lead author and the director of the Lymphoma Immunotherapy Program at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai. “This method could also increase the success of other immunotherapies such as checkpoint blockade.”

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MeiraGTx’s founders were interested in those uses; the biotech’s programs today are in diseases of the eye, salivary gland and brain.

But “we wanted to have a broader perspective on how you could potentially use gene therapy” too, CEO Alexandria Forbes says.

That vision is a high-tech, futuristic one, in which the human body can essentially become a medicine-making factory, enabled by gene therapy. But it’ll require more research, and is still years from fruition.

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“Smart” contact lenses sound like something from a sci fi movie — but they’re real, and they could help troops in the field.


French engineering school IMT Atlantique revealed what it calls “the first stand-alone contact lens with a flexible micro battery” earlier this month.

And, notably, it caught the attention of the U.S. military’s attention: the Defense Advanced Research Projects Agency (DARPA) is reportedly interested in the contact lens to augment troops’ visual capabilities in the field, according to Task and Purpose — meaning the gadget could represent the augmented contact lens that DARPA has spent a decade searching for.

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