Lifeboat Foundation

In a new study, researchers show that the presence of senescent cells is an important contributor to aging of the cardiovascular system, particularly the heart [1].

Senescent cells and senolytics

As your body ages, increasing amounts of your cells enter into a state of senescence. Senescent cells do not divide or support the tissues of which they are part; instead, they emit a range of potentially harmful inflammatory chemical signals, which are known as the senescence associated secretory phenotype (SASP). The SASP can also encourage other nearby healthy cells to also enter the same senescent state.

Continue reading “Senolytics Improve Recovery Following a Heart Attack” »

Tune in beginning at 6:30 a.m. EDT on Monday, as Anne McClain of NASA and David Saint-Jacques of the Canadian Space Agency set up a redundant power supply for the station’s robotic arm. Watch live coverage here:

Learn about the BIG potential of microreactors.

Together, deep learning and symbolic reasoning create a program that learns in a remarkably humanlike way.

Reaction Engines, which is based in Oxfordshire, has tested their new pre-cooler’ technology — which allows aircraft to travel faster than ever with a Sabre engine designed to take planes into orbit.

Chinese space has been a very hot topic in recent years. Other than the impressive space exploration missions (Tiangong, Chang’e…), the interest for China is also due to the recent opening up of this industry to private investments, which has led to a leap in the number of space start-ups. These start-ups, supported by venture capital heavy-weights are covering the entire space industrial chain: launchers, satellite platforms, satellite subsystems, satellite services, ground segment, etc.

The number of space start-ups on the other hand, is a debated question. Chen Lan estimated in November 2018 that there were over 100 Chinese space start-ups [1]. FutureAerospace, a Beijing-based think-tank, sets the number at around 60, at the same period [2]. Other space watchers have suggested 80 such as in [3]. However, how this count is made is rarely detailed (how do we define a “NewSpace company”?), and very few lists are available at the time of writing, if any. Up to now, only Disrupt Space, a start-up which plans to build a global space entrepreneurial community, has undertaken the establishment of a list, which sets the count at 35 Chinese space start-ups (see map below).

Fig. 1 – Disrupt Space’s Chinese Space Start-up Mapping in November 2018 [4]

Continue reading “China’s NewSpace: Mapping of its 60+ Start-ups” »

Hydrazine rocket fuel is highly toxic, carcinogenic and unstable, making it incredibly dangerous to work with. Scientists at McGill believe their new alternative, based on metal-organic frameworks, will lead to cleaner, safer, more controllable rockets.

Beauty might only be skin deep, but for those wondering how to keep that skin young, scientists may have found an answer in the form of a protein that encourages cell competition.

The prosaically named COL17A1 might not sound like a fountain of youth, but the new study suggests it does the heavy lifting when it comes to keeping skin intact and unimpaired.

The protein works by encouraging cell competition, a key process to maintain tissue fitness. That effectively “drives out” weaker cells while encouraging replication of stronger ones.

Continue reading “Forever young: study uncovers protein that keeps skin youthful” »

Fresh interview with Aubrey de Grey

What is ageing? We can define ageing as a process of accumulation of the damage which is just a side-effect of normal metabolism. While researchers still poorly understand how metabolic processes cause damage accumulation, and how accumulated damage causes pathology, the damage itself — the structural difference between old tissue and young tissue — is categorized and understood pretty well. By repairing damage and restoring the previous undamaged — young — state of an organism, we can really rejuvenate it! It sounds very promising, and so it is. And for some types of damage (for example, for senescent cells) it is already proved to work!

Today in our virtual studio, somewhere between cold, rainy Saint-Petersburg and warm, sunny Mountain View, we meet Aubrey de Grey, again! For those of you who are not familiar with him, here is a brief introduction.

Continue reading “Finally, rejuvenation is a thing!” »