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Feb 20, 2019

Deep Space Climate Observatory

Posted by in categories: climatology, space travel

https://www.youtube.com/watch?v=t3_1Ju5knGU&pbjreload=10

A NASA camera aboard the Deep Space Climate Observatory (DSCOVR) satellite captured a unique view of the moon as it moved in front of the sunlit side of Earth last month. The series of test images shows the fully illuminated ‘dark side’ of the moon that is never visible from Earth. The images were captured by NASA’s Earth Polychromatic Imaging Camera (EPIC), a four megapixel CCD camera and telescope on the DSCOVR satellite orbiting 1 million miles from Earth. From its position between the sun and Earth, DSCOVR conducts its primary mission of real-time solar wind monitoring for the National Oceanic and Atmospheric Administration (NOAA). EPIC maintains a constant view of the fully illuminated Earth as it rotates, providing scientific observations of ozone, vegetation, cloud height and aerosols in the atmosphere. Once EPIC begins regular observations next month, the camera will provide a series of Earth images allowing study of daily variations over the entire globe. About twice a year the camera will capture the moon and Earth together as the orbit of DSCOVR crosses the orbital plane of the moon. These images were taken between 12:50 p.m. and 5:45 p.m. PDT on July 16, showing the moon moving over the Pacific Ocean near North America. The North Pole is in the upper left corner of the image, reflecting the orbital tilt of Earth from the vantage point of the spacecraft. EPIC’s ‘natural color’ images of Earth are generated by combining three separate monochrome exposures taken by the camera in quick succession. EPIC takes a series of 10 images using different narrowband spectral filters — from ultraviolet to near infrared — to produce a variety of science products. The red, green and blue channel images are used in these color images. Combining three images taken about 30 seconds apart as the moon moves produces a slight but noticeable camera artifact on the right side of the moon. Because the moon has moved in relation to the Earth between the time the first (red) and last (green) exposures were made, a thin green offset appears on the right side of the moon when the three exposures are combined. This natural lunar movement also produces a slight red and blue offset on the left side of the moon in these unaltered images. The lunar far side lacks the large, dark, basaltic plains, or maria, that are so prominent on the Earth-facing side. The largest far side features are Mare Moscoviense in the upper left and Tsiolkovskiy crater in the lower left. A thin sliver of shadowed area of moon is visible on its right side.

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Feb 20, 2019

Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients

Posted by in category: biotech/medical

Autologous induced pluripotent stem cells (iPSCs) constitute an unlimited cell source for patient-specific cell-based organ repair strategies. However, their generation and subsequent differentiation into specific cells or tissues entail cell line-specific manufacturing challenges and form a lengthy process that precludes acute treatment modalities. These shortcomings could be overcome by using prefabricated allogeneic cell or tissue products, but the vigorous immune response against histo-incompatible cells has prevented the successful implementation of this approach. Here we show that both mouse and human iPSCs lose their immunogenicity when major histocompatibility complex (MHC) class I and II genes are inactivated and CD47 is over-expressed. These hypoimmunogenic iPSCs retain their pluripotent stem cell potential and differentiation capacity. Endothelial cells, smooth muscle cells, and cardiomyocytes derived from hypoimmunogenic mouse or human iPSCs reliably evade immune rejection in fully MHC-mismatched allogeneic recipients and survive long-term without the use of immunosuppression. These findings suggest that hypoimmunogenic cell grafts can be engineered for universal transplantation.

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Feb 20, 2019

China’s Greater Bay Area still has hurdles to clear if it wants to be a tech challenger to Silicon Valley

Posted by in categories: education, engineering, policy

However, a shortage of hi-tech research capacity in the region is turning into a hindrance, according to analysts, with most of China’s top-notch science and engineering schools located in the northern and eastern provinces. Although Hong Kong has several universities in the world’s top 100, only a few of them have a science and technology focus.


China’s ‘Greater Bay Area’ plan aims to erase barriers between cities in the region in terms of policy, financing, logistics and talent.

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Feb 19, 2019

Explainer: What is quantum communication?

Posted by in categories: business, cybercrime/malcode, health, quantum physics

Barely a week goes by without reports of some new mega-hack that’s exposed huge amounts of sensitive information, from people’s credit card details and health records to companies’ valuable intellectual property. The threat posed by cyberattacks is forcing governments, militaries, and businesses to explore more secure ways of transmitting information.

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Feb 19, 2019

A 10x Innovation Framework Enabling Powerful Future Growth

Posted by in categories: innovation, singularity

Get Singularity University’s innovation framework to enable powerful future growth. Christine Kelly, Managing Director, Innovation & Design at SUfour key steps that enable organizations to leap from ideation to delivering breakout solutions and growth that will drive sustained success.

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Feb 19, 2019

Single-dose CRISPR–Cas9 therapy extends lifespan of mice with Hutchinson–Gilford progeria syndrome

Posted by in categories: biotech/medical, genetics, life extension

Hutchinson–Gilford progeria syndrome (HGPS) is a rare lethal genetic disorder characterized by symptoms reminiscent of accelerated aging. The major underlying genetic cause is a substitution mutation in the gene coding for lamin A, causing the production of a toxic isoform called progerin. Here we show that reduction of lamin A/progerin by a single-dose systemic administration of adeno-associated virus-delivered CRISPR–Cas9 components suppresses HGPS in a mouse model.

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Feb 19, 2019

Star Wars’ porgs can be your virtual pets on Magic Leap One

Posted by in category: futurism

You can feed your porgs and play fetch with a Chewbacca doll.

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Feb 19, 2019

Trump signs new directive calling on Space Force to be part of the Air Force

Posted by in category: space

It won’t be a separate branch.


Not exactly the ‘separate but equal’ branch that was originally planned.

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Feb 19, 2019

Slowing the Aging Process

Posted by in categories: biotech/medical, genetics, life extension, neuroscience

It’s inevitable in life, but aging isn’t really something people look forward to. Researchers have been seeking ways to reduce the impact of aging, not only because of vanity but also because as we age, there is a greater risk of certain serious health conditions like cancer, heart disease and neurodegenerative conditions like Alzheimer’s disease. Salk Institute scientists have now used CRISPR/Cas9, the gene-editing tool, to slow down aging. The work, reported in Nature Medicine, showed accelerated aging can be slowed in mice modeling a rare genetic disorder called Hutchinson-Gilford progeria syndrome.

“Aging is a complex process in which cells start to lose their functionality, so it is critical for us to find effective ways to study the molecular drivers of aging,” said the senior author of the report Juan Carlos Izpisua Belmonte, a professor in Salk’s Gene Expression Laboratory. “Progeria is an ideal aging model because it allows us to devise an intervention, refine it and test it again quickly.”

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Feb 19, 2019

Scientists create new map of brain’s immune system

Posted by in categories: biotech/medical, neuroscience

“We were able to show that there is only a single type of microglia in the brain that exist in multiple flavours,” says project head Prof. Dr. Marco Prinz, medical director of the Institute of Neuropathology at the Medical Center — University of Freiburg. “These immune cells are very versatile all-rounders, not specialists, as has been the textbook opinion up to now,” sums up Prof. Prinz.


A team of researchers under the direction of the Medical Center — University of Freiburg has created an entirely new map of the brain’s own immune system in humans and mice. The scientists succeeded in demonstrating for the first time ever that the phagocytes in the brain, the so-called microglia, all have the same core signature but adopt in different ways depending on their function. It was previously assumed that these are different types of microglia. The discovery, made by means of a new, high-resolution method for analyzing single cells, is important for the understanding of brain diseases. Furthermore, the researchers from Freiburg, Göttingen, Berlin, Bochum, Essen, and Ghent (Belgium) demonstrated in detail how the human immune system in the brain changes in the course of multiple sclerosis (MS), which is significant for future therapeutic approaches. The study was published on 14. February 2019 in the journal Nature.

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