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On the frontlines of the Ebola response are local Congolese workers with temporary job contracts. They are often driven into this work by economic necessity, as well as a desire to help.

Belinda Landu, a tall 28-year-old with long hair who radiates confidence, was making a meager living as a tailor in capital city Kinshasa before the outbreak. While visiting her mother in Beni last August, she spotted an advertisement for a health promoter. Today, she’s passionate about her role: decontaminating the houses of confirmed Ebola patients. “I want to stop the spread of the epidemic,” she said. “My family understand I work here to help people. If we get Ebola people will help us too.”

When she arrives at the scene of a recent diagnosis, Landu changes into a full protective outfit, including a full plastic bodysuit, mask, hairnet, gumboots, and both latex and rubber gloves, and begins the slow process of covering everything — inside and outside a house — with a chlorinated spray. Locals gather around to stare at her. They’re often terrified, she says, though she tries to be kind — speaking to them before she starts, and even stopping to play soccer with children after she changes out of her outfit.

Dr. Oliver Medvedik and guests will be taking a look at the recent human trial of Urolithin A, a metabolite produced by microflora and an active ingredient in pomegranates which is linked to increased levels of mitophagy in aged animals. Join us at 13:00 EDT on our Facebook channel where we will be livestreaming the show and discussing this interesting publication.

Link to Paper: https://www.nature.com/articles/s42255-019-0073-4

Literature.

Nature asked researchers and other stakeholders what hurdles remain before heritable gene editing could become acceptable as a clinical tool. Although some scientific challenges are probably surmountable, approval on a grand scale is likely to require changes to how clinical trials are run, as well as a broader consensus about the technology.


Efforts to make heritable changes to the human genome are fraught with uncertainty. Here’s what it would take to make the technique safe and acceptable.