Initial participants may spend 28 days in these ‘sentinels’—but the firm envisions much, much longer stays.
NASA’s Hubble Space Telescope has captured a cosmic bullseye. The gargantuan galaxy LEDA 1,313,424 is rippling with nine star-filled rings after an “arrow”—a far smaller blue dwarf galaxy—shot through its heart. Astronomers using Hubble identified eight visible rings, more than previously detected by any telescope in any galaxy, and confirmed a ninth using data from the W. M. Keck Observatory in Hawaii. Previous observations of other galaxies show a maximum of two or three rings.
“This was a serendipitous discovery,” said Imad Pasha, the lead researcher and a doctoral student at Yale University in New Haven, Connecticut. “I was looking at a ground-based imaging survey and when I saw a galaxy with several clear rings, I was immediately drawn to it. I had to stop to investigate it.” The team later nicknamed the galaxy the “Bullseye.”
Hubble and Keck’s follow-up observations also helped the researchers prove which galaxy plunged through the center of the Bullseye—a blue dwarf galaxy to its center-left. This relatively tiny interloper traveled like a dart through the core of the Bullseye about 50 million years ago, leaving rings in its wake like ripples in a pond. A thin trail of gas now links the pair, though they are currently separated by 130,000 light-years.
Apple has been ordered by the U.K. to provide officials access to users’ encrypted accounts, the Washington Post reported Friday.
Leo P, a small galaxy and a distant neighbor of the Milky Way, is lighting the way for astronomers to better understand star formation and how a galaxy grows.
In a study published in the Astrophysical Journal, a team of researchers led by Kristen McQuinn, a scientist at the Space Telescope Science Institute and an associate professor in the Department of Physics and Astronomy at the Rutgers University-New Brunswick School of Arts and Sciences, has reported finding that Leo P “reignited,” reactivating during a significant period on the timeline of the universe, producing stars when many other small galaxies didn’t.
By studying galaxies early in their formation and in different environments, astronomers said they may gain a deeper understanding of the universe’s origins and the fundamental processes that shape it.
For decades there has been near constant progress in reducing the size, and increasing the performance, of the circuits that power computers and smartphones. But Moore’s Law is ending as physical limitations – such as the number of transistors that can fit on a chip and the heat that results from packing them ever more densely – are slowing the rate of performance increases. Computing capacity is gradually plateauing, even as artificial intelligence, machine learning and other data-intensive applications demand ever greater computational power.
Novel technologies are needed to address this challenge. A potential solution comes from photonics, which offers lower energy consumption and reduced latency than electronics.
One of the most promising approaches is in-memory computing, which requires the use of photonic memories. Passing light signals through these memories makes it possible to perform operations nearly instantaneously. But solutions proposed for creating such memories have faced challenges such as low switching speeds and limited programmability.
Xenon gas inhalation reduced neurodegeneration and boosted protection in preclinical models of Alzheimer’s disease. Most treatments being pursued today to protect against Alzheimer’s disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research from Mass General Brigham and Washington University School of Medicine in St. Louis points to a novel — and noble — approach: using Xenon gas. The study found that Xenon gas inhalation suppressed neuroinflammation, reduced brain atrophy, and increased protective neuronal states in mouse models of Alzheimer’s disease. Results are published in Science Translational Medicine, and a phase 1 clinical trial of the treatment in healthy volunteers will begin in early 2025.
“It is a very novel discovery showing that simply inhaling an inert gas can have such a profound neuroprotective effect,” said senior and co-corresponding author Oleg Butovsky, PhD, of the Ann Romney Center for Neurologic Diseases at Brigham and Women’s Hospital (BWH), a founding member of the Mass General Brigham healthcare system. “One of the main limitations in the field of Alzheimer’s disease research and treatment is that it is extremely difficult to design medications that can pass the blood-brain barrier — but Xenon gas does. We look forward to seeing this novel approach tested in humans.”
“It is exciting that in both animal models that model different aspects of Alzheimer’s disease, amyloid pathology in one model and tau pathology in another model, that Xenon had protective effects in both situations,” said senior and co-corresponding author David M. Holtzman, MD, from Washington University School of Medicine in St. Louis.
Researchers have demonstrated, for the first time in the world using mice, the ability to overcome significant challenges in gene therapy using adeno-associated virus vectors (AAV), specifically “production of neutralizing antibodies” and “hepatotoxicity,” by employing a novel smart nanomachine equipped with AAV.
The research results are published in the journal ACS Nano.
The co-first authors of the paper are Assistant Professor Yuto Honda from the Laboratory for Chemistry and Life Science at the Institute of Science Tokyo. Dr. Hiroaki Kino, a Principal Research Scientist at iCONM, and Prof. Nishiyama are listed as corresponding authors alongside Prof. Honda, while other researchers from iCONM are acknowledged as co-authors.
Humans are not yet done cooking. We’re continuing to evolve and adjust to the world around us, the records of our adaptations written in our bodies.
We know that there are some environments that can make us unwell. Mountain climbers often succumb to altitude sickness – the body’s reaction to a significant drop in atmospheric pressure, which means less oxygen is taken in with each breath.
And yet, in high altitudes on the Tibetan Plateau, where oxygen levels in the air people breathe are notably lower than lower altitudes, human communities thrive.