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The ESA BioRock space experiment was carried into orbit, bound for the International Space Station (ISS), on 25 July 2019 as part of the SpaceX CRS-18 mission. CRS-18 lifted off from Space Launch Complex 40 (SLC-40) at Cape Canaveral Air Force Station, Florida, aboard a Falcon 9 launcher. The experiment will investigate the growth of biofilms and their ability to extract minerals and use them as nutrients (biomining) in microgravity conditions. This will be directly compared with results obtained under Mars and Earth gravity conditions simulated using a centrifuge on the ISS. The findings will contribute towards a better understanding of the growth of microorganisms in space, which is also key to bioregenerative life support systems, the formation of biofilms and microbial ore extraction. In future, such processes could be used in the biomining of economically valuable chemical elements such as copper on other planets. The German Aerospace Center (Deutsches Zentrum für Luft- und Raumfahrt; DLR) is playing a key role in the experiment.

Three species of bacteria are being investigated in the BioRock experiment: Sphingomonas desiccabilis, Bacillus subtilis and Cupriavidus metallidurans. “Our research focuses on the organism Bacillus subtilis,” says Petra Rettberg from the DLR Institute of Aerospace Medicine. “We are curious to see how well this bacterium can extract nutrients from the minerals of the basalt that was inoculated with Bacillus spores for the space experiment.” Over the coming weeks, the experiment will be put into operation on the ISS and is expected to remain in space until the end of August 2019. The experiment will then return to Earth for analysis and evaluation, with the samples later being examined in the astrobiological laboratories at the DLR site in Cologne.

Biofilms are among the oldest visible signs of life on Earth and could also perhaps be found to be the earliest forms of life on other planets and moons in the Solar System. A biofilm is a structured community of microorganisms on a surface, encapsulated in a self-formed matrix made of extracellular polymeric substances (EPS). This EPS matrix holds the microorganisms together in their three-dimensional arrangement and enables the biofilm to adhere to surfaces. The properties of microorganisms living within a biofilm generally differ substantially from those of microorganisms of the same species existing independently. The dense environment of the film allows them to cooperate with one another, interact in many ways and protects these minute organisms from external influences. This means that microorganisms in biofilms are highly resistant to various chemical and physical effects and can be used for a range of applications in space.

Longevity investor and visionary Sergey Young, founder of Longevity Vision Fund and Innovation Board Member of XPRIZE Foundation, delivers “7 Signs of Longevity Revolution” keynote at Barclay’s recent “Accelerating Evolution” conference, discussing recent developments in the longevity industry.

Watch to find out the forecasts for the industry’s trajectory of growth in the coming years, the increasing emergence of practical, real-world applications in the longevity sphere and how Longevity Vision Fund striving to be on the very forefront of the ongoing Longevity Revolution that is already happening around us today.

#longevity #lvf #longevityvisionfund #lifeextension #longevityrevolution #sergeyyoung #barclays

The art of tattooing may have found a diagnostic twist. A team of scientists in Germany have developed permanent dermal sensors that can be applied as artistic tattoos. As detailed in the journal Angewandte Chemie, a colorimetric analytic formulation was injected into the skin instead of tattoo ink. The pigmented skin areas varied their color when blood pH or other health indicators changed.

Researchers from the Beijing Institute of Brain Disorders have discovered a new method of using exosomes to deliver aptamers that prevent the accumulation of α-synuclein aggregates, which are the cause of Parkinson’s disease [1].

α-Synuclein Aggregates

Like Alzheimer’s, Parkinson’s disease is characterized by protein aggregation caused by a loss of proteostasis, one of the hallmarks of aging. In order for the brain to function properly, non-aggregated α-synuclein proteins are needed in order to facilitate the release of dopamine, a neurotransmitter, in nerve cell synapses. α-synuclein only becomes a problem when proteostasis fails and the proteins misfold, aggregate, and accumulate.