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The Curious Case of Sickle-Cell Anemia

Even those uninterested in biology have likely heard of the disorder. Sickle-cell anemia holds the crown as the first genetic disorder to be traced to its molecular roots nearly a hundred years ago.

The root of the disorder is a single genetic mutation that drastically changes the structure of the oxygen-carrying protein, beta-globin, in red blood cells. The result is that the cells, rather than forming their usual slick disc-shape, turn into jagged, sickle-shaped daggers that damage blood vessels or block them altogether. The symptoms aren’t always uniform; rather, they come in “crisis episodes” during which the pain becomes nearly intolerable.

Excellent interview:


Dr. Gerald Parker Associate Dean for Global One Health at Texas A&M and Professor Andrew S Natsios Executive Professor at The Bush School and Director of the Scowcroft Institute of International Affairs have a sit down with Patrick Bet-David about the Coronavirus Pandemic. About our guests Dr. Gerald Parker https://bit.ly/2IZPRAl Professor Andrew S. Natsios https://bit.ly/2UkWBy6

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