A recent study suggests that circulating glucuronic acid may be a useful predictor of both lifespan and healthspan in humans and mice.
What is glucuronic acid?
Glucuronic acid is a metabolite of glucose and is critical for the detoxification of xenobiotic substances. These are compounds that are not naturally produced, should not normally be in the body, or are present in higher concentrations than normal.
From the brain to AI :
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In the last video in this series we discussed the differences between deep learning and machine learning, how and when the field of deep learning was officially born, and it’s rise to mainstream popularity. The focus of this video then will be on artificial neural networks, more specifically – their structure.
ROBOTS will be assisting surgeons to carry out complex medical procedures within ten years, offering just one example of how the rapidly evolving scientific field will change the world as the 21st century progresses, a robotic engineer has predicted.
Research led by University of Texas at Dallas physicists has altered the understanding of the fundamental properties of perovskite crystals, a class of materials with great potential as solar cells and light emitters.
Published in July in Nature Communications, the study presents evidence that questions existing models of the behavior of perovskites on the quantum level.
“Our enhanced understanding of the physics of perovskites will help determine how they are best used,” said Dr. Anton Malko, associate professor of physics in the School of Natural Sciences and Mathematics and a corresponding author of the paper.
Researchers from the University of Maryland, the National Institute of Standards and Technology (NIST), the National High Magnetic Field Laboratory (NHMFL) and the University of Oxford have observed a rare phenomenon called re-entrant superconductivity in the material uranium ditelluride. The discovery furthers the case for uranium ditelluride as a promising material for use in quantum computers.
Nicknamed “Lazarus superconductivity” after the biblical character who rose from the dead, the phenomenon occurs when a superconducting state arises, breaks down, then re-emerges in a material due to a change in a specific parameter—in this case, the application of a very strong magnetic field. The researchers published their results on October 7, 2019, in the journal Nature Physics.
Once dismissed by physicists for its apparent lack of interesting physical properties, uranium ditelluride is having its own Lazarus moment. The current study is the second in as many months (both published by members of the same research team) to demonstrate unusual and surprising superconductivity states in the material.
HUNTSVILLE, Alabama – Moon propellant mining outposts can grow into lunar cities. A futuristic architecture promises to greatly reduce the cost of human exploration and industrialization of Earth’s celestial next-door-neighbor.
“The future belongs to those who prepare for it today.”–Malcolm X “Be open-minded, but not so open-minded that your brains fall out.”–Groucho Marx In our …
William G. Kaelin, Jr., of the Dana-Farber Cancer Institute and Harvard University, Sir Peter J. Ratcliffe, of Oxford University and the Francis Crick Institute, and Gregg L. Semenza, of Johns Hopkins University were jointly awarded the prize.
The complex interplay of various processes and mechanisms that contribute to aging means it’s unlikely we’ll discover a single “magic bullet” to prevent age-related diseases. But new research led by University College London and the Max Planck Institute for Biology and Ageing is potentially as close as anything we’ve seen. The scientists have been able to extend the lifespan of fruit flies by 48 percent using a triple drug combination made up of drugs already used in people.
“As life expectancies increase, we are also seeing an increase of age-related diseases so there is an urgent need to find ways to improve health in old age,” says study co-lead author, Dr Jorge Castillo-Quan. “Here, by studying fruit flies which age much more rapidly than people, we have found that a combination drug treatment targeting different cellular processes may be an effective way to slow down the aging process.”
The three drugs making up the combo include lithium, which is used as a mood stabilizer, trametinib, a cancer drug that inhibits MEK1 and MEK2 enzymes, and rapamycin, an immune system regulator produced by bacteria that was first found in a soil sample from Easter Island and has been found to improve learning and memory in mice.
