Toggle light / dark theme

De novo genes are even prompting a rethink of some portions of evolutionary theory. Conventional wisdom was that new genes tended to arise when existing ones are accidentally duplicated, blended with others or broken up, but some researchers now think that de novo genes could be quite common: some studies suggest at least one-tenth of genes could be made in this way; others estimate that more genes could emerge de novo than from gene duplication. Their existence blurs the bou…


Scientists long assumed that new genes appear when evolution tinkers with old ones. It turns out that natural selection is much more creative.

After years in the wilderness, Halo: The Master Chief Collection will bring Halo Reach, Halo: Combat Evolved Anniversary, Halo 2: Anniversary, Halo 3: ODST (minus the Firefight mode), Halo 3 and Halo 4 to PC.

The only previous games in the FPS series to launch on PC were Halo and Halo 2, both well over a decade ago (if you don’t count the Halo Wars spin-offs). This is obviously a big moment, and it seems like Microsoft is making some good decisions in bringing them to PC: Namely launching them on Steam, rather than trapping them on the Microsoft Store (though you can buy it there too). There’s much more to go into below, too.

The PC version is being worked on by Halo stewards 343 Industries, Ruffian Games and Splash Damage. In total, the Master Chief Collection will entail over 120 multiplayer maps and 67 campaign missions—which should be enough to keep you occupied for a while. The idea is to “evolve and grow” the collection over time with community input, so it’s likely we’ll see more features added to each game after launch.

He lay in a hospital bed at the University of Arkansas, stricken with a rare disease. His blood platelet count was so low that even a slight bump to his body could trigger a lethal brain bleed. A doctor told him to write his living will on a piece of paper.

Fajgenbaum was rushed to a CT scan. Tears streamed down his face and fell on his hospital gown. He thought about the first patient who’d died under his care in medical school, and how her brain had bled in a similar way from a stroke.

He didn’t believe he’d live out the scan.